New Drugs Approved in 2007

Synthetic approaches to the 2007 new drugs.

New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the syntheses of 19 NCEs marketed in 2007.

How safe are new drugs? Market withdrawal of drugs approved in Canada between 1990 and 2009

BACKGROUND Studying drugs withdrawn from the market for safety reasons can help in evaluating the strengths and weaknesses of the pre- and post-market safety evaluation systems. This study considered 2 questions: Has there been a change over time in the percentage of new drugs that are eventually withdrawn because of safety reasons? How long are new drugs on the market before their serious safe...

Current approved drugs for aquatic species.

A quaculture is an important developing international industry. Approved pharmaceutical agents available to veterinarians in the United States are limited in their therapeutic scope and efficacy. Ensuring preharvest food safety and preventing illegal drug residues are extremely important issues in the selection of therapeutic regimens for aquatic species. Currently available therapeutic substan...

FDA-Approved Drugs to Treat Schizophrenia.

FDA approved drugs as potential Ebola treatments

In the search for treatments for the Ebola Virus, multiple screens of FDA drugs have led to the identification of several with promising in vitro activity. These compounds were not originally developed as antivirals and some have been further tested in mouse in vivo models. We put forward the opinion that some of these drugs could be evaluated further and move into the clinic as they are alread...